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Project

Human Cell Atlas of the Female Reproductive System


Focus Reproductive
Method Single Cell Transcriptomics

Project Summary

This project will establish a human cell atlas of the female reproductive system, focusing on the ovaries, fallopian tube, and uterus.


Results & Resources

This group developed new techniques for fallopian tube and myometrium single-cell dissociation, oocyte and live follicle isolation, and single-cell isolation from the ovary to generate a comprehensive atlas of the female reproductive system. They generated an atlas of the fallopian tube and identified two new cell types. Additional analyses identified 11 cell types in the myometrium and endometrium, and more than 20 cell types across ovarian cells.


Investigators

Co-Principal Investigators
Sue Hammoud, PhD
Sue Hammoud, PhD
Jun Z. Li, PhD
Jun Z. Li, PhD

Erica Marsh, MD, MSCI
Erica Marsh, MD, MSCI
Ariella Shikanov, PhD
Ariella Shikanov, PhD