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Project

Spatiotemporal Multi-Organ Developmental Maps from the Same Individual

Focus Multiple Organs
Method Multiomics, Single Cell Transcriptomics, Spatial Proteomics

Project Summary

This project will build a spatiotemporal atlas of a single individual’s multi-organ developmental program by applying integrated single-cell RNA-seq and 4i spatial maps to primary tissue and matched iPSC-derived organoids from the same individual.

Investigators

Co-Principal Investigators
Gray Camp, PhD
Gray Camp, PhD
Institute of Molecular and Clinical Ophthalmology Basel (IOB)
Switzerland
Smita Krishnaswamy, PhD
Smita Krishnaswamy, PhD
Yale School of Medicine
United States

ORCID

0000-0001-5823-1985
Prisca Liberali, PhD
Prisca Liberali, PhD
Friedrich Miescher Institute for Biomedical Research (FMI)
Switzerland

ORCID

0000-0003-0695-6081
Lucas Pelkmans, PhD
Lucas Pelkmans, PhD
University of Zurich
Switzerland
Jason Spence, PhD
Jason Spence, PhD
University of Michigan
United States

ORCID

0000-0001-7869-3992
Barbara Treutlein, PhD
Barbara Treutlein, PhD
Swiss Federal Institute of Technology in Zurich
Switzerland

ORCID

0000-0002-3299-5597