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Autoantibody Biomarkers of Messenger RNA Defects in Neurodegeneration


Award Collaborative Pairs Pilot Project Awards (Cycle 2) (Phase 1)
Focus Area Neurodegeneration

Project Description

to evaluate whether TDP-43 loss-of-function-related cryptic mis-splicing results in autoantibodies to aberrant neoepitopes in patients with frontotemporal lobar degeneration.


Investigators

William Seeley, MD
William Seeley, MD
Michael Wilson, PhD
Michael Wilson, PhD