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Autoantibody Biomarkers of Messenger RNA Defects in Neurodegeneration

Award Collaborative Pairs Pilot Project Awards (Cycle 2) (Phase 1)
Focus Area Neurodegeneration

Project Description

to evaluate whether TDP-43 loss-of-function-related cryptic mis-splicing results in autoantibodies to aberrant neoepitopes in patients with frontotemporal lobar degeneration.

Investigators

William Seeley, MD
William Seeley, MD

University of California, San Francisco

Michael Wilson, MD, PhD
Michael Wilson, MD, PhD

University of California, San Francisco

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