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RNA-Protein Interaction Sequencing for Tandem Repeat Disorders

Award Collaborative Pairs Pilot Project Awards (Cycle 2) (Phase 1)
Focus Area Neurodegeneration

Project Description

to study the sequestration of RNA binding proteins as a common pathogenic mechanism of neurodegeneration in tandem repeat disorders using a transformative new technology that leverages genome editing tools.

Investigators

Mandana Arbab, PhD
Mandana Arbab, PhD

Boston Children’s Hospital

Richard Sherwood, PhD
Richard Sherwood, PhD

Brigham and Women’s Hospital

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