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Small RNA-Bound Amyloid Beta Aggregates in Human Alzheimer’s Disease Brain

Award Collaborative Pairs Pilot Project Awards (Cycle 2) (Phase 1)
Focus Area Neurodegeneration

Project Description

to combine biochemical study of postmortem Alzheimer’s disease brain tissue with new extracellular RNA analysis to define the RNA-bound diffusible amyloid beta complex and its toxicity.

Investigators

Ryan Flynn, MD, PhD
Ryan Flynn, MD, PhD

Boston Children’s Hospital

Andrew Stern, MD, PhD
Andrew Stern, MD, PhD

Brigham and Women’s Hospital

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