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Project

Human Lung Cell Atlas 1.0


Focus Respiratory
Method Epigenetic Sequencing, Single Cell Transcriptomics, Spatial Genomics, Spatial Proteomics

Project Summary

This network will create the first version of the Human Lung Cell Atlas by developing and extending computational methods to allow the integration of single cell and spatial transcriptomics, microscopy, and other data types.

Creating a lung atlas that will be broadly useful as a reference for understanding diseases such as asthma will require integrating samples from varying ages and ethnicities. This project will build upon the existing collection of pediatric airway and lung samples to include additional Black and Asian pediatric samples from across five age groups and multiple locations in the lung.

This Network was awarded the CZI Seed Networks Incentive to Support Diversity for the Human Cell Atlas.


Investigators

Co-Principal Investigators
Alexander Misharin, MD, PhD
Alexander Misharin, MD, PhD
Alexander Tsankov, PhD
Alexander Tsankov, PhD

Douglas Shepherd, PhD
Douglas Shepherd, PhD
Fabian Theis, PhD
Fabian Theis, PhD

Herbert B. Schiller, PhD
Herbert B. Schiller, PhD
Jayaraj Rajagopal, MD
Jayaraj Rajagopal, MD

Jeffrey Whitsett, MD
Jeffrey Whitsett, MD
Joseph Powell, PhD
Joseph Powell, PhD

Kerstin Meyer, PhD
Kerstin Meyer, PhD
Mark Krasnow, MD, PhD
Mark Krasnow, MD, PhD

Marko Nikolic, MD, PhD
Marko Nikolic, MD, PhD
Martijn Nawijn, PhD
Martijn Nawijn, PhD

Naftali Kaminski, MD
Naftali Kaminski, MD
Oliver Eickelberg, MD
Oliver Eickelberg, MD

Pascal Barbry, PhD
Pascal Barbry, PhD
Purushothama Rao Tata, PhD
Purushothama Rao Tata, PhD

Thu Elizabeth Duong, MD
Thu Elizabeth Duong, MD
Tushar Desai, MD
Tushar Desai, MD

Collaborators
Dana Pe'er
Dana Pe'er