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Project

Human Vascular Endothelial Cell Atlas in the Young and Old


Focus Cardiovascular
Method Single Cell Transcriptomics, Spatial Genomics

Project Summary

This network is contributing to an endothelial cell atlas in space and time by mapping the transcriptomes of endothelial cells from several tissues from donors of different ages and developing cutting-edge computational tools. To expand the racial diversity of this atlas, the project will include samples from Black and Latinx donors, which will help to clarify how cardiovascular disease manifests differently among various populations.

This Network was awarded the CZI Seed Networks Incentive to Support Diversity for the Human Cell Atlas.


Investigators

Co-Principal Investigators
Zhen Chen, PhD, BMed
Zhen Chen, PhD, BMed
Guo-Cheng Yuan, PhD
Guo-Cheng Yuan, PhD

Xuegong Zhang, PhD
Xuegong Zhang, PhD
Zemin Zhang, PhD
Zemin Zhang, PhD

Sheng Zhong, PhD
Sheng Zhong, PhD
Collaborators
Mingxia Gu, MD, PhD
Mingxia Gu, MD, PhD
Zhenglong Gu, PhD
Zhenglong Gu, PhD