Project
Single-Cell Epigenomics and Transcriptomics of the Childhood Brain
Award
Pediatric Networks
Project Summary
This project will create a comprehensive cell atlas of the childhood brain by performing joint chromatin and transcriptome profiling at single-cell resolution of healthy tissues from five brain regions and seven donors.
This resource, which will be open to the entire research community through the Human Cell Atlas, will address a lack of a reference for the childhood brain and a lack of representation of the admixed Brazilian genetic background in current references. It will be invaluable for the study of the early stages of brain development and brain-related diseases affecting children.
Investigators
Co-Principal Investigators
![Diogo Troggian Veiga, PhD](https://chanzuckerberg.com/wp-content/uploads/2021/08/IMG_20210819_152400_2-e1629918366115.jpeg)
Diogo Troggian Veiga, PhD
![Fernando Cendes, MD, PhD](https://chanzuckerberg.com/wp-content/uploads/2021/08/Photo-Fernando-Cendes-e1629918420798.jpeg)
Fernando Cendes, MD, PhD
![Claudia Kleinman, PhD](https://chanzuckerberg.com/wp-content/uploads/2021/08/Kleinman_Peds2021-e1629918438615.jpeg)
Claudia Kleinman, PhD
![Iscia Lopes-Cendes, MD, PhD](https://chanzuckerberg.com/wp-content/uploads/2021/08/Iscia-e1629918394375.jpeg)
Iscia Lopes-Cendes, MD, PhD