Autoantibody Biomarkers of Messenger RNA Defects in Neurodegeneration
Award
Collaborative Pairs Pilot Project Awards (Cycle 2) (Phase 1)
Focus Area
Neurodegeneration
Project Description
to evaluate whether TDP-43 loss-of-function-related cryptic mis-splicing results in autoantibodies to aberrant neoepitopes in patients with frontotemporal lobar degeneration.
Investigators
William Seeley, MD
Michael Wilson, MD, PhD