Pediatric Networks for the Human Cell Atlas
These projects support researchers to contribute pediatric tissue samples to the global Human Cell Atlas as a foundation for understanding how cells and organs mature and relate to disease onset in children. Read our Medium post.
Showing 18 results
This team will build a single-cell pediatric atlas of healthy peripheral blood myeloid and lymphoid cell development, following Bacillus Calmette-Guérin (BCG) vaccine induced trained immunity in the first year of life.
David Lissauer Louise Afran Simon van Heeringen Kondwani Kawaza Anmol Kiran Benjamin Kumwenda Sam Lissauer Musa M. Mhlanga Yutaka Negishi Mihai Netea
This team hopes to understand the single-cell biology of the nasopharyngeal and oral mucosa in children living within globally representative communities.
Jose Ordovas-Montanes Thushan de Silva Sarah Glover Wanda Gonzalez Bruce Horwitz Partha Majumder Senjuti Saha Abdul Sesay Alex K. Shalek Corrine Sin Quee-Brown Lael M. Yonker
This team will develop a roadmap of pediatric ovarian maturation to better understand gonadal pathophysiology.
Roser Vento-Tormo Sheila Lane Virgine Uhlmann Suzannah Williams
This project seeks to generate an atlas of adipose tissue from donors of different ancestries in abdominal, subcutaneous, and cardiac depots, which are known contributors to child and adult health.
Carey Lumeng Samir Gadepalli Richard Ohye Kanakadurga Singer Joshua D. Welch Susan Woolford
This team will build a single-cell atlas of the pediatric intestine to understand how the human intestine matures in childhood and adult intestinal diseases.
Alison Simmons Paul Johnson Hashem Koohy
This team will build a longitudinal heart atlas from infant, childhood, and adolescent tissues across multiple ancestries.
Christine Seidman Kenneth Campbell Matthias Heinig Norbert Hübner Hendrik Milting Michela Noseda Gavin Oudit Sebastian Pott William Pu
This team will develop a comprehensive immune and epithelial cell atlas of the healthy pediatric airway as an open-access reference for understanding globally significant childhood lung diseases.
Melanie Neeland Eric Levi Jovana Maksimovic Boris Novakovic Alicia Oshlack Sarath Ranganathan Richard Saffery Shivanthan Shanthikumar
This team will examine the complexity and maturation of human tissue and pluripotent stem cell-derived organoid models, which are essential for modeling human organ homeostasis and pediatric diseases.
Jason Spence Grayson Camp Gail Deutsch Barbara Treutlein
This team will map early gut development across populations with diverse ancestry, and examine social determinants of health and environmental exposures.
Jay Thiagarajah Phyllis Bishop Imran Nisar Kamran Sadiq Jocelyn Silvester Piotr Sliz Scott Snapper Sana Syed
This project will create an ancestrally diverse, open access, multi-omic atlas of the nose, mouth, and airways from birth through adolescence.
James Hagood Richard Boucher Kevin Matthew Byrd Arjun Guha Michelle Hernandez Adam Kimple Scott Randell Herbert Schiller Purushothama Rao Tata Fabian Thies
This team will produce an interactive single-cell genome and spatial browser so datasets are accessible across sites and to the wider scientific community.
Arnold Kriegstein Arturo Alvarez-Buylla Omer Bayraktar Eric Huang Tomasz Nowakowski Mercedes Paredes Xianhua Piao Elizabeth Rogers David Rowitch Fabian Theis
This team will combine single-cell, single-nucleus, and spatial transcriptomics, integrating the results to establish a robust reference atlas throughout pediatric skeletal muscle development.
Monkol Lek Rachel Alvarez Alan Beggs Carsten Bönnemann Yi-wen Chen Benjamin Cosgrove Jordi Diaz-Manera Jyoti Jaiswal Douglas Millay Steven Moore Angela Viaene
This team will generate a comprehensive spatially resolved, single-cell atlas of human pediatric ocular tissue.
John Timothy Stout Rui Chen Margaret DeAngelis Mingyao Li Jeffrey Moffitt
This project will transform current knowledge of human organ development and maturation, paving the way to discover new therapeutics, with a direct benefit to pediatric and adult health.
Marko Nikolic Anna David Sara Hillman Thomas Jacques Kerstin Meyer
This team will analyze liver tissue through stages of normal pediatric development across diverse ancestries and build single-cell maps to share with the scientific community that define cell types, transcriptional heterogeneity, and spatial organization of a healthy liver.
Alan Mullen Gary Bader Alex Cuenca Stacey S. Huppert Sonya MacParland Krupa Mysore Charlotte Scott Sarah Taylor Ramnik Xavier
This team will develop a comprehensive cell atlas of the childhood brain by performing joint chromatin and transcriptome profiling at single-cell resolution of healthy tissues.
Diogo Troggian Veiga Fernando Cendes Claudia Kleinman Iscia Lopes-Cendes
This team will generate and analyze foundational data from healthy samples necessary to provide insights relevant for pediatric inflammatory and infectious skin conditions, genetic skin diseases, and disorders specific to historically marginalized communities.
Muzlifah Haniffa Dave Horsfall Edel O’Toole Bayanne Olabi Neil Rajan Inês Sequeira Mirjana Efremova
This team will develop a comprehensive, time- and space-resolved multi-omic single-cell atlas of the developing hematopoietic and immune system that benefits the entire scientific and clinical community.
Kathrin Bernt Pablo Gonzalez Camara Jeffrey Gerber Sarah E. Henrickson Amy Kratchman Neil Romberg Kai Tan Laura Vella Hao Wu
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