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Project

Single-Cell Epigenomics and Transcriptomics of the Childhood Brain


Award Pediatric Networks

Project Summary

This project will create a comprehensive cell atlas of the childhood brain by performing joint chromatin and transcriptome profiling at single-cell resolution of healthy tissues from five brain regions and seven donors.

This resource, which will be open to the entire research community through the Human Cell Atlas, will address a lack of a reference for the childhood brain and a lack of representation of the admixed Brazilian genetic background in current references. It will be invaluable for the study of the early stages of brain development and brain-related diseases affecting children.


Investigators

Co-Principal Investigators
Diogo Troggian Veiga, PhD
Diogo Troggian Veiga, PhD
Fernando Cendes, MD, PhD
Fernando Cendes, MD, PhD

Claudia Kleinman, PhD
Claudia Kleinman, PhD
Iscia Lopes-Cendes, MD, PhD
Iscia Lopes-Cendes, MD, PhD