Our vision with CZI’s Open Science program is the universal and immediate open sharing of all scientific knowledge, processes, and outputs. Over the next 10 years, we aim to support a diverse scientific community working in the open to accelerate our understanding of human health and disease. We invest in tools, platforms, and organizations that help expand participation and access to the scientific process by making it open and reproducible, and helping scientists build on each others’ work.
Tools & Resources for Research
We fund open source tools and technology that support the computational and reproducibility needs of biomedical researchers. We support the maintainers and creators of these tools and efforts to increase diversity and inclusion in their ranks.
Education & Capacity Building
We support work that increases awareness about the benefits of open science and ensures researchers are trained to effectively engage in open science practices and computational reproducibility.
Metrics & Incentives
We support projects that help shift incentives toward rewarding open science practices in biomedical research.
Improved Infrastructure Technology & Integration
We support improvements to existing infrastructure, interoperability, standardization, and accessibility among systems used by scientists and research contributors.
Meet Our Grantees
Our work aims to accelerate the pace of scientific progress. Part of that is making sure researchers have access to reliable information and sustainable open source infrastructure. We support platforms where researchers can quickly and openly disseminate methods, tools, preprints (scientific papers published prior to peer review), and other research outputs. We also partner with organizations contributing to the infrastructure underlying open science and serving the needs of communities around the world.
We support sharing platforms that enable accessing and sharing research processes and open outputs easily, and as early as possible in the research cycle.
Education & Capacity Building Grants
We support training and education for researchers to engage in open science best practices.
Communities of Practice Grants
We partner with organizations that foster communities of practice for groups underrepresented in science and technology.
Essential Open Source Software for Science
Open source software is crucial to modern scientific research, advancing biology and medicine while providing reproducibility and transparency. Yet even the most widely-used research software often lacks dedicated funding. CZI’s Essential Open Source Software for Science program supports software maintenance, growth, development, and community engagement for critical open source tools.
Open Science Team
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Request for Applications
Essential Open Source Software for Science (Cycle 5)
This RFA supports the maintenance, growth, development, and community engagement of open source software projects to help make the computational foundations of biological research more usable and robust.
- Cycle 1 - $5 Million
- Cycle 2 - $3.8 Million
- Cycle 3 - $3 Million
- Cycle 4 - $11.1 Million
- Cycle 5 - $12.5 Million
News & Stories
Interested in learning more about our work in open science? Get the latest information from the links below.
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Join Our Team
Explore our job openings.
Explore Our Grant Resources
Read our Request for Applications.