About Us

The Chan Zuckerberg Initiative supports the science and technology to make it possible to cure, prevent and manage all disease in this century. Founded in 2015, CZI helps solve some of society's toughest challenges.

Our Leadership
See Careers
Inside a lab with modern instruments and monitors visible, a scientist in a blue lab coat gestures toward a large piece of equipment while two visitors lean in to observe closely.
Angela Detweiler, a scientist at the Chan Zuckerberg Biohub San Francisco, briefs Chan Zuckerberg Initiative cofounders and co-CEOs Priscilla Chan and Mark Zuckerberg on the lab’s genome sequencing instruments. | Photo by Cody Pickens for Forbes
Angela Detweiler, a scientist at the Chan Zuckerberg Biohub San Francisco, briefs Chan Zuckerberg Initiative cofounders and co-CEOs Priscilla Chan and Mark Zuckerberg on the lab’s genome sequencing instruments. | Photo by Cody Pickens for Forbes

Our Science Focus

We bring scientists, engineers, and AI and machine learning experts together to tackle complex scientific grand challenges.

Biohub Network & Institutes

Our institutes do cutting-edge science that cannot be done in conventional environments. By pairing scientists with experts from a variety of disciplines, we pursue scientific grand challenges at the intersection of AI and biology to improve human health.

Learn more.

Technology

Our Science Technology team accelerates the pace of biomedical research by building models, methods, tools, applications, and datasets for scientists. Our technology-driven approach helps researchers come to meaningful conclusions about human health and disease.

Learn more.

Research

We produce and support scientific research to advance our mission, engaging deeply with the scientific and technology communities to accelerate research and promote open science. Explore publications and preprints from across our institutes and grant partners.

Learn more.

Supporting Our Work

Across our work in science and education, and within our communities, we pair technology with our research and grantmaking, impact investing, and collaboration to help accelerate the pace of progress toward our mission.

Two CZI Science Technology team members working together in front of a laptop computer.
Technology
We are a new kind of philanthropic organization focused on engineering change at scale. Our engineering team partners with issue experts across our science, education, and strategic partners to help bring technology to the table in new ways that drive solutions.
Learn more.
"Ventures at CZI" team member meeting with developers in Africa (Grants & Ventures).
Grants & Ventures
Through grantmaking and our venture portfolio, we invest in bold ideas that have the potential to accelerate change. Since 2015, CZI has awarded approximately $6.98 billion in grants and invested nearly $300 million in ventures whose work aligns with our values.
Learn more.
Two women seated at a table listen during a group conversation, with other people gathered in the background.
Education
We want to ensure that every student can get an education that’s tailored to their individual needs and supports every aspect of their development. And we want every teacher to be equipped with the tools and research they need to help get them there.
Learn more.
People mingle and talk around a table with coffee and flowers at a community gathering.
Community
We support work to create greater opportunity for communities in the Bay Area and across California, which includes flexible, responsive grantmaking; and partnerships around key issues, like housing affordability and homelessness.
Learn more.

CZI is composed of four funding entities: the Chan Zuckerberg Initiative, LLC (the main operational funding vehicle); the Chan Zuckerberg Initiative Foundation (a 501(c)(3) private foundation); the Chan Zuckerberg Initiative Donor-Advised Fund (DAF) at the Silicon Valley Community Foundation; and Chan Zuckerberg Initiative Advocacy, (a 501(c)(4) organization).