Molecularly-Defined Neural Cells Altered by Alzheimer’s Disease Pathology

Award Collaborative Pairs Pilot Project Awards (Cycle 2) (Phase 1)

Focus Area Neurodegeneration

Project Description

to establish the impact of Alzheimer’s disease pathology on molecularly-defined neural cells during cognitive tasks using sequentially-coupled calcium imaging with spatial transcriptomics.

Investigators

Joseph Castellano, PhD

Icahn School of Medicine at Mount Sinai

Herbert Wu, PhD

Icahn School of Medicine at Mount Sinai