A Pilot Tertiary Analysis Portal for the Human Cell Atlas

To implement pipelines for tertiary analyses of Human Cell Atlas datasets and develop associated, community-driven standards for the supported tools.

The Papatheodorou lab, in collaboration with Kerstin Meyer’s group, developed a Galaxy-based interactive computation platform for the tertiary analysis of single-cell RNA-seq data. The platform allows flexible construction of analysis workflows by linking computation steps, such as pre-processing, clustering and differential expression analysis, in a drag-and-drop fashion. Additionally, they created pre-made workflows and implemented data retrieval from the Human Cell Atlas Data Coordination Platform matrix service and the EBI Single-Cell Expression Atlas.