Our Leadership

Priscilla Chan is co-founder and co-CEO of the Chan Zuckerberg Initiative. As a pediatrician and teacher, Priscilla’s work with patients and students in communities across the Bay Area has informed her desire to make learning more personalized, find new paths to manage and cure disease, and expand opportunity for more people. She is also the founder of The Primary School, which integrates health and education and serves children and families in East Palo Alto and the Belle Haven neighborhood in Menlo Park, California. Priscilla earned her bachelor's degree in biology at Harvard University and her Doctor of Medicine at University of California, San Francisco (UCSF). She completed her pediatrics residency training in the UCSF Pediatric Leaders Advancing Health Equity program.

Marc Malandro is the chief operating officer of the Chan Zuckerberg Initiative and the CZ Biohub Network, where he is focused on optimizing operations across all of the organizations in the CZ Science ecosystem. Marc started as the vice president for science operations and helped build the science program and science team at CZI. Before coming to CZI, Marc served at the University of Pittsburgh as the vice chancellor for technology management and commercialization and the founding director of the Innovation Institute, whose mission was to create, support and sustain a culture of innovation, entrepreneurship and collaboration on campus. Prior to joining the university, Marc co-founded Sagres Discovery, a systems biology company focused on the understanding of the molecular basis of cancer. Marc received his bachelor's and master's in biological sciences and Doctor of Science from Youngstown State University. He also holds a doctorate in biochemistry and molecular biology from the University of Florida College of Medicine.

Patricia Brennan is the vice president of science technology at the Chan Zuckerberg Initiative. Prior to joining CZI, Patricia held leadership roles at Clarivate and Thomson Reuters, where she led product design, product management and platform development. She is also a product coach and advisor to individuals and organizations, where she assists them in honing and growing their product management practices. Patricia has a master's in library and information science from the Catholic University of America and a bachelor's in English literature from the University of Maryland, College Park.

As the Chan Zuckerberg Initiative’s chief investment officer, David Lee is responsible for managing CZI’s investment portfolio, which funds the organization’s efforts across science, education, and within our communities. David came to CZI from the Princeton University Investment Company where he worked on asset allocation and the marketable asset categories, including domestic equity, international equity and independent return. Prior to Princeton, David worked at ABN AMRO in London, England. He earned a first-class honors degree in economics and econometrics from the University of York, holds a Master of Science with distinction specializing in quantitative finance from the University of Reading, and received an MBA from the Yale School of Management. He is a CFA Institute charterholder.