Computational Tools for Traversing Genes to Cells to Disease
To pioneer the development of methods and software to understand differences in how cells behave, and to implement these in Hail, a scalable software platform designed for biological analysis.
Results & Resources
This project addressed the larger goal of adapting and extending Hail, the scalable infrastructure the Neal lab built for genetics, to the problem of single-cell RNA-seq method development and data analysis. They designed and implemented a user level python interface for n-dimensional arrays adapted to fit into the existing Hail interface and extended the representation to include n-d array and linear algebra primitives.