Single-Cell Analysis of Inflammation

CZI’s Inflammation program supports a network of researchers studying how inflammation influences disease in cells and tissues. Knowing more about inflammation will increase our understanding of many diseases such as asthma, arthritis, and heart disease—and improve our ability to cure, prevent, and manage them.

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Showing 29 results

A Data-Driven Approach to Understanding Liver and Lung Diseases
Investigators Cole Trapnell, PhD (University of Washington)
Bruce Trapnell, MS, MD (Cincinnati Children's Hospital Medical Center)
Yiing Lin, MD (Washington University in St. Louis)
Focus Fibrosis, Liver, Lung
Analyzing How Inflammation Affects the Aging Brain
Investigators Anne Brunet, PhD (Stanford University)
Ami Bhatt, MD, PhD (Stanford University)
Chris Garcia, PhD (Stanford University)
Focus Aging, Microbiome, Modeling, Neuroimmune, Tools & Technologies
Deciphering Inflammatory Memory in Wound Healing
Investigators Giacomo Donati, PhD (University of Torino)
Ken Natsuga, MD, PhD (Hokkaido University Hospital)
Tzachi Hagai, PhD (Tel Aviv University)
Focus Skin
Decoding Inflammation through Immune Cell Behavior
Investigators Eduardo Reategui, PhD (Ohio State University)
Tim Laemmermann, PhD (Max Planck Institute of Immunobiology and Epigenetics)
Focus Tools & Technologies
Decoding Inter-Organ Inflammatory Signaling at the Single-Cell Level
Investigators Nicolas Chevrier, PhD (The University of Chicago)
Andrew Ferguson, PhD (The University of Chicago)
Savas Tay, PhD (The University of Chicago)
Focus Tools & Technologies
Exploring Single-Cell Sequencing of Liver Inflammation
Investigators Bruce Wang, MD (University of California, San Francisco)
Michele Tana, MD, MHS (University of California, San Francisco)
Focus Liver
High-Resolution Profiling of Body Fat Immune Cells in Brazilian Populations
Investigators Marcelo Alves da Silva Mori, PhD (University of Campinas, Brazil)
Mariana Boroni, MSc, PhD (Brazilian National Cancer Institute)
Pedro Moraes-Vieira, DVM, PhD (University of Campinas, Brazil)
Focus Immunology, Obesity
How the Gut and Nervous System Control the Spread of Infection
Investigators James Gagnon, PhD (University of Utah)
Kristen Kwan, PhD (University of Utah)
Nels Elde, PhD (University of Utah)
Focus Neuroimmune
How Western Lifestyles Modify Immune Responses in East African Populations
Investigators Julien Ayroles, PhD (Princeton University)
Brittany Adamson, PhD (Princeton University)
Michael Mina, MD, PhD (Harvard University)
Focus Genetic Diversity
Identifying Neuroimmune Mechanisms Triggered by the Flu
Investigators Colin Reardon, PhD (University of California, Davis)
Nicole Baumgarth, DVM, PhD (University of California, Davis)
Focus Lung, Neuroimmune
Imaging Gut Immune Cells and Microbes to Understand Health and Disease
Investigators Lucy Erin O'Brien, PhD (Stanford University)
Kerwyn Casey Huang, MPhil, PhD (Stanford University)
Focus Gut, Microbiome, Modeling, Tools & Technologies
Inflammation in Pediatric Pulmonary Diseases
Investigators Melanie Neeland, PhD (Murdoch Children’s Research Institute)
Alicia Oshlack, PhD (Peter MacCallum Cancer Centre)
Sarath Ranganathan, MB ChB, MRCP, FRCPCH, FRACP, PhD (Murdoch Children’s Research Institute)
Focus Lung, Tools & Technologies
Investigating Similarities and Differences Between Chronic and Acute Inflammation
Investigators Marcelo Dietrich, MD, PhD (Yale University)
Andrew Wang, MD, PhD (Yale University)
Noah Palm, PhD (Yale University)
Focus Gut, Metabolism, Microbiome, Neuroimmune
Local Inflammation in Atherosclerosis
Investigators Chiara Giannarelli, MD, PhD (Icahn School of Medicine at Mount Sinai)
Dan Avi Landau, MD, PhD (Weill Cornell Medicine, New York Genome Center)
Minji Byun, PhD (Icahn School of Medicine at Mount Sinai)
Focus Aging, Cardiovascular, Tools & Technologies
Mapping Human Inflammatory Responses in Ethnically Diverse Groups
Investigators Anita Milicic, MSc, DPhil (University of Oxford)
Calliope Dendrou, PhD (University of Oxford)
Mark Coles, PhD (University of Oxford)
Focus Vaccine Adjuvants
Mapping Skin Inflammation in Rare Disease Patients
Investigators John Tsang, PhD (National Institute of Allergy and Infectious Diseases, National Institutes of Health)
Rachel Sparks, MD, MPH (National Institute of Allergy and Infectious Diseases, National Institutes of Health)
Ronald Germain, MD, PhD (National Institute of Allergy and Infectious Diseases, National Institutes of Health)
Focus Modeling, Skin
Probing the Role of Inflammation in Heart Regeneration
Investigators Robin Choudhury, MA, DM, FRCP (University of Oxford)
Mathilda Mommersteeg, PhD (University of Oxford)
Paul Riley, PhD (University of Oxford)
Focus Cardiovascular
Single-Cell Approaches to Decipher Central Nervous System Trauma
Investigators Jony Kipnis, PhD (Washington University School of Medicine in St. Louis)
Kodi Ravichandran, PhD (University of Virginia)
Focus Neuroimmune
Studying Vascular Disease in Diverse Patients
Investigators Joseph Wu, MD, PhD (Stanford University)
Elsie Gyang Ross, MD (Stanford University)
Philip S. Tsao, PhD (Stanford University)
Focus Aging, Cardiovascular, Genetic Diversity
Tools to Manipulate Gene Expression in 3D Models of Human Disease
Investigators Nicole Coufal, MD, PhD (University of California, San Diego)
Christopher Glass, MD, PhD (University of California, San Diego)
Gene Yeo, PhD, MBA (University of California, San Diego)
Focus Neuroimmune
Understanding How Age Influences Susceptibility to Coronavirus Infection
Investigators Vineet Menachery, PhD (University of Texas Medical Branch at Galveston)
Andrew Routh, PhD (University of Texas Medical Branch at Galveston)
Focus Aging, Lung, Tools & Technologies, Viral Infection
Understanding How Maternal Inflammation Impacts Pregnancy
Investigators Kellie Ann Jurado, PhD (University of Pennsylvania)
Dan Dongeun Huh, PhD (University of Pennsylvania)
Monica Mainigi, MD (University of Pennsylvania)
Focus Maternal & Fetal Health
Understanding How Stress and Social Disparity Affect Preterm Birth
Investigators Jingjing Li, PhD (University of California, San Francisco)
David K. Stevenson, MD (Stanford University)
Gary M. Shaw, DrPH (Stanford University)
Focus Maternal & Fetal Health
Understanding Inflammation’s Role in Childhood Obesity
Investigators Jorge Henao-Mejia, MD, PhD (University of Pennsylvania)
Golnaz Vahedi, PhD (University of Pennsylvania)
Sarah Henrickson, MD, PhD (Children’s Hospital of Philadelphia, University of Pennsylvania )
Focus Obesity
Understanding Organism-Wide Inflammation After Heart Injury
Investigators James Lo, MD, PhD (Weill Cornell Medicine)
Doron Betel, PhD (Weill Cornell Medicine)
Jingli Cao, PhD (Weill Cornell Medicine)
Focus Cardiovascular
Understanding Pediatric Inflammatory Bowel Disease
Investigators Hiutung Chu, PhD (University of California, San Diego )
David Gonzalez, PhD (University of California, San Diego )
Mamata Sivagnanam, MD (University of California, San Diego | Rady Children’s Hospital, San Diego)
Focus 3D Models, Gut, Microbiome
Understanding the Impact of Urbanization on Immune Systems in Rural and Urban Africa
Investigators Ahmed Mahfouz, PhD (Leiden University Medical Center)
Maria Yazdanbakhsh, PhD (Leiden University Medical Center)
Moustapha Mbow, PhD (Cheikh Anta Diop University)
Focus Immune, Tools & Technologies
Unraveling Neuroimmune Interactions at the Single-Cell Level
Investigators Isaac Chiu, PhD (Harvard Medical School)
Henrique Veiga-Fernandes, PhD (Champalimaud Center for the Unknown )
Stephen Liberles, PhD (Harvard Medical School, Howard Hughes Medical Institute)
Focus Neuroimmune
Visualizing B- and T-cell Clones Associated in Autoimmunity
Investigators Jeffrey Moffitt, PhD (Boston Children's Hospital)
Michael Carroll, PhD (Boston Children's Hospital)
Focus Autoimmunity, Tools & Technologies

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