Correlative Cryo-Fluorescence Microscopy and Electron Tomography in Tissues
Award Imaging Scientist
Funding Cycle Cycle 2
Georg Ramm, PhD
Monash University (Monash Ramaciotti Centre for Cryo-Electron Microscopy)
Georg Ramm is the head of the Monash Ramaciotti Centre for Cryo-Electron Microscopy at Monash University in Melbourne, Australia. He trained as a microscopist, cell biologist, and biochemist during a PhD at Utrecht University in the Netherlands, and during undergraduate and diploma degrees in Germany. He established the Monash Ramaciotti Centre, which serves both cell and structural biologists and is Australia’s first high-end cryo-EM facility with a Titan Krios microscope. He has developed, applied, and taught advanced imaging techniques with a focus on correlative light and electron microscopy and cryo-EM.
Cryo-electron tomography bridges cell and structural biology. This project aims to develop workflows for cryo-tomography in tissues so that researchers can study tissues’ molecular architecture in health and disease. Georg Ramm will work directly with collaborators to use cryo-tomography to answer fundamental biomedical questions. He will use hands-on learning to teach these new techniques to cell and structural biologists.