Neurodegeneration Challenge Network

Neurodegenerative diseases, like Alzheimer’s, Parkinson’s, ALS, and Huntington’s Disease, are a leading cause of death and disability worldwide. There are no effective therapies to prevent, cure, or treat most of these disorders. To make progress, we’ve developed a new kind of collaborative network — one that brings new ideas and new people into the field, supports them with well-validated tools and resources, and asks them to look at this problem from a cross-disease perspective.

The Neuroscience program was launched in 2018 with a focus on neurodegenerative disease and centered on the CZI Neurodegeneration Challenge Network (NDCN). The Challenge Network model is built on the vision that progress in solving neurodegenerative diseases will come from bringing new talent and ideas from diverse disciplines and expertise into the neurodegeneration field, building interdisciplinary collaborations, empowering the broader scientific community with robust tools and platforms, and creating a culture of innovation, collaboration, and open science.

An outline of a human body, with words surrounding the body– words read “early career researchers”, “foundational biology”, “tools and technology”, “open science”, “culture and collaboration”, “patient organizations”, “collaborative research teams”, and “CZI teams”.

Understanding Neurodegeneration

Meet more than 70 grantees studying a variety of neurodegenerative diseases

A woman stands in front of an easel with large sheets of paper and speaks to several meeting participants.
CZI Neurodegeneration Challenge Network early career grantee Molly Gale Hammell presents to Network members at a meeting.

Neurodegeneration Challenge Network Mentors

CZI values the critical role that mentors and mentorship play in career development. We are grateful for the contributions of the Neurodegeneration Challenge Network Mentors who provide mentorship for the Ben Barres Early Career Acceleration Award grantees, empowering them to reach their full scientific and professional potential.

Learn About Our Mentors

Our Strategic Partners

We’re proud to work alongside a number of distinguished organizations that share our goals of providing high quality resources for the neuroscience community.