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The Innate Immune System in Neurodegeneration

Award Ben Barres Early Career Acceleration Awards (Cycle 1)
Focus Area Neurodegeneration

Project Description

Our scientific goal is twofold. First, we want to understand the pathogenic mechanisms of mutant proteins in neurodegeneration. Second, we aim to test the hypothesis that neurodegenerative diseases can be instigated or accelerated by dysfunction of the innate immune system. Our study has an important therapeutic implication, as its findings may provide a rationale for targeting the innate immune system to decelerate or even eradicate neurodegenerative diseases.


Ivan Marazzi, PhD
Ivan Marazzi, PhD