Grant Resources for Scientific Research
We support science through targeted grantmaking and open competitions for research funds in specific issue areas with Requests for Applications, or RFAs. Read about current and past science grant opportunities below and visit our Newsroom and Medium for updates on our grantees.
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Funding Opportunities: Request for Applications (RFAs)
Showing 25 results
Request for Applications
Science Diversity Leadership Award
This RFA supports excellent biomedical researchers with a record of promoting diversity, equity, and inclusion in their scientific field.
- Total Grant Resources 2022 Cohort $28.75 Million
Request for Applications
Rare as One
Rare As One (Cycle 3)
This RFA supports patient-led nonprofit organizations as they launch collaborative research networks and work together to accelerate progress against rare diseases.
- Cycle 3 - $24 Million
Request for Applications
Cell Science
Single-Cell Biology Data Insights
This grant program seeks to support computational experts to advance tools and resources that make it possible to gain greater insights into health and disease from single-cell biology datasets.
- Total Grant Resources - $14.9 Million
- Cycle 1: - $5.2 Million
- Cycle 2 - $4.9 Million
- Cycle 3: - $4.8 Million
- Total Grant Resources - $14.9 Million
Request for Applications
Open Science
Essential Open Source Software for Science (Cycle 6)
In partnership with The Kavli Foundation and The Wellcome Trust, this CZI program supports software maintenance, growth, development, and community engagement for critical open source scientific tools.
- Cycle 6 - $11.7 Million (with Kavli Foundation and Wellcome Trust)
Request for Applications
Imaging
Cryo-CLEM Labels
This grant program aims to drive development of complete, general-purpose, intracellular imaging probes for cryo-correlative light and electron microscopy (cryo-CLEM).
- Total Grant Resources $1.5 Million
Request for Applications
Imaging
Deep Tissue Imaging (Phases 1-2)
This grant program aims to drive development of innovative imaging technologies that will advance the field of deep tissue imaging, allowing researchers to observe cells and subcellular processes at high resolution in complex tissue and through skin and bone.
- Phase 2 - $19.6 Million
Request for Applications
Neurodegeneration Challenge Network
Collaborative Pairs Pilot Project Awards (Cycle 2)
This RFA supports pairs of investigators and their teams to explore innovative, interdisciplinary approaches to address critical challenges in the fields of neurodegenerative diseases and fundamental neuroscience.
- Cycle 2 - $12.8 million
Request for Applications
Cell Science
Measuring Metabolism Across Scales
This RFA aims to accelerate innovative discoveries in the field of metabolism and metabolic physiology in health and disease.
- Total Grant Resources $8.6 Million
Request for Applications
Neurodegeneration Challenge Network
Ben Barres Early Career Acceleration Awards (Cycles 1-2)
This RFA aims to provide mentored support for early career investigators to conduct bold, innovative, and rigorous research in the basic science underlying neurodegenerative disease and fundamental neuroscience.
- Cycle 2 - $15.6 Million
Request for Applications
Imaging
Advancing Imaging Through Collaborative Projects
This RFA supports new and existing collaborative projects to reduce imaging ecosystem fragmentation and accelerate the spread and adoption of technologies, methods, or training resources.
- Total Grant Resources $5 Million
Request for Applications
Imaging
Dynamic Imaging
This RFA aims to advance technology directed at real-time visualization of biological processes at the level of cells and molecules.
- Total Grant Resources $19.8 Million
Request for Applications
Imaging
napari Plugin Grants
This grant program will support software plugin development projects for the napari image analysis platform, a community-built, open source, and interactive tool for Python designed for browsing, annotating, and analyzing large multi-dimensional images.
- Cycle 2 - $875,000
Request for Applications
Cell Science
Patient-Partnered Single-Cell Analysis of Rare Pediatric Disease RFA
This RFA aims to support the application of single-cell biology methods to rare inflammatory pediatric diseases that will clarify cellular mechanisms of disease, understand disease heterogeneity, and improve biomarker identification or diagnostics.
- Total Grant Resources $10 Million
Request for Applications
Neurodegeneration Challenge Network
Patient-Partnered Rare Neurodegenerative Disease RFA
This RFA aims to advance the understanding of the pathophysiology and mechanistic underpinnings of rare neurodegenerative and neurological disorders.
- Total Grant Resources $10 Million
Request for Applications
Chan Zuckerberg Biohub Network
This funding opportunity supports scaling the Chan Zuckerberg Biohub model to pursue the toughest and most important scientific challenges by bringing together leading U.S.-based scientific and technology institutions within close geographical proximity to each... This funding opportunity supports scaling the Chan Zuckerberg Biohub model to pursue the toughest and most important scientific challenges by bringing together leading U.S.-based scientific and technology institutions within close geographical proximity to each other.
Request for Applications
Imaging
Expanding Global Access to Bioimaging
This grant program supports imaging science capacity building, fellowships, and community development for imaging core facilities and nonprofit organizations in Africa, Latin America and the Caribbean, and former Soviet countries.
- Total Grant Resources $4.1 Million
Request for Applications
Cell Science
Ancestry Networks for the Human Cell Atlas
This RFA supports researchers to contribute healthy, single-cell reference data from ancestrally diverse tissue samples to the Human Cell Atlas, with the aim of creating a more globally representative resource to understand disease.
- Total Grant Resources $28 Million
Request for Applications
Cell Science
Pediatric Networks for the Human Cell Atlas
This grant program supports researchers to contribute pediatric tissue samples to the global Human Cell Atlas as a foundation for understanding how cells and organs progress and relate to disease onset in children.
- Total Grant Resources $33 million
Request for Applications
Imaging
Visual Proteomics Imaging
This RFA supports challenge grants in visual proteomics, with the goal of advancing technology that will enable researchers to view protein molecules and their interactions inside cells at near-atomic resolution.
- Total Grant Resources $27.5 Million
Request for Applications
Imaging
Imaging Scientists Cycles 1-2
This RFA supports CZI Imaging Scientists at imaging centers worldwide who will leverage biology, microscopy hardware, and imaging software to accelerate biomedicine and improve the imaging tools scientists use.
- - $10.2 Million
Request for Applications
Cell Science
Single-Cell Analysis of Inflammation
This RFA supports interdisciplinary scientists as they apply new tools and work together in accelerating inflammation research. With these research grants, we aim to further our understanding of inflammation’s role in maintaining health and triggering disease.
- Total Grant Resources $14 million
Request for Applications
Cell Science
Seed Networks for the Human Cell Atlas
This RFA supports the continued development of the Human Cell Atlas, a global effort to map all cells in the human body.
- Total Grant Resources $68 Million
Request for Applications
Neurodegeneration Challenge Network
Collaborative Science Awards
As part of the CZI Neurodegeneration Challenge Network, an interdisciplinary collaborative network that addresses fundamental issues in neurodegenerative disease biology, these are grant opportunities for small group interdisciplinary research collaborations tha... As part of the CZI Neurodegeneration Challenge Network, an interdisciplinary collaborative network that addresses fundamental issues in neurodegenerative disease biology, these are grant opportunities for small group interdisciplinary research collaborations that include a physician with active clinical engagement.
- Total Grant Resources $9 Million
Request for Applications
Cell Science
Collaborative Computational Tools for a Human Cell Atlas
This program awards grants to spur the creation of new computational tools, algorithms, visualizations, and benchmark datasets to analyze, interpret, and disseminate a large variety of molecular and imaging data generated for the global Human Cell Atlas.
- Total Grant Resources $15 million
Request for Applications
Cell Science
Pilot Projects for a Human Cell Atlas
This program awards scientific grants to support the Human Cell Atlas community’s convergence around standards, protocols, and best practices for the creation of a freely and openly available reference database of healthy human cells and tissues.
- Total Grant Resources $15 million
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