Innovations in scientific imaging technologies such as ultrasound, MRI, photoacoustic, optical, X-ray, and quantum imaging could be transformative for biomedical applications and for understanding life at the cellular level. The Frontiers of Imaging effort supports technology development to allow researchers to peer deep into tissues in order to better understand and cure disease. Read more.
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This project will achieve transformations in X-ray tomography technology by enabling cellular-level imaging anywhere in whole organisms, including human bodies, providing insight at multiple anatomical levels.
This project will develop genetically encodable biomolecular tools that will enable ultrasound to image specific cellular functions deep inside the body.
This project will use a novel, multidisciplinary approach aimed at overcoming the current limitations of wavefront shaping microscopy to enable truly deep biological imaging.
This team will apply new computational microscopy techniques to reconstruct a sample’s 3D light scattering potential and digitally correct scattering effects.
This project will pioneer short-wave infrared multiphoton microscopy, transforming intravital microscopy into a non-invasive technology.
This project will revolutionize the imaging depth with light at optical wavelength resolution by developing a new type of microscopy that uses nonlinear holography for ultradeep tissue imaging.
This project will use high-speed camera and laser technology to create contactless ultrasound arrays, able to image centimeters into tissue and at cellular resolution.
This project will develop new ultrasound techniques for deep tissue imaging of cell types, cellular interactions, and cancers.
This team will develop magnetic resonance microscopy that combines novel data acquisition approaches, image reconstructions, gradient and cryogenic radiofrequency coil technologies, and ultra-high field strength to obtain unique cellular information in disease models.
This project will develop a comprehensive toolbox of genetic near-infrared photochromic photoacoustic probes, acoustic-tunnel enhanced light delivery, and stochastic localization of photoacoustic probes in order to push the resolution limit of photoacoustic imaging.
This project will develop quantum multi-photon excitation microscopy for centimeter-scale deep tissue imaging in complex organisms.
This project will develop new near-infrared emitters and dual infrared 2-photon imaging technologies for deep tissue subcellular-scale imaging in brain and plant tissues.
This project will develop and validate a super-resolution photoacoustic imaging technology using a revolutionary ultrasensitive nanophotonic sensor that enables single-cell resolution molecular imaging at centimeter depth in vivo.
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