CZI | How We Support Science

Is it possible to cure, prevent, or manage all diseases by the end of this century? We think so. In the last 100 years, biomedical science has made tremendous strides in advancing human health and treating disease, but much more can be achieved in the years to come. We seek to accelerate progress by awarding grants for scientific research that can advance entire fields, building and funding transformative technologies in partnership with the scientific community, and fostering interdisciplinary collaborations in science. Learn how CZI supports its Science work.

Over the next decade, CZI Science is focused on developing new research, institutes, and technologies to measure and observe human biology in new ways to help deepen our understanding of human health and disease.

Our Science Programs

We work in areas where we think we can make a differentiated impact through supporting technology development, interdisciplinary research collaborations, and partnerships. Learn about our work in science.

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Imaging

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Neurodegeneration Challenge Network thumbnail photo of neurons.

Neurodegeneration  Challenge Network

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Open Science

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Science in Society

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Single-Cell Biology thumbnail photo of cell structure.

Single-Cell Biology

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Learn More About Our Programs

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Technology

We aim to help make every scientist a better scientist by improving the tools and technologies they rely on every day. We work closely with researchers to understand their challenges and build solutions for the scientific community.

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CZ GEN EPI

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Chan Zuckerberg Biohub

In September 2016, Priscilla Chan and Mark Zuckerberg announced CZI’s first big scientific bet with the Chan Zuckerberg Biohub (CZ Biohub), a unique research institution that brings together scientists and engineers from Stanford University; University of California, Berkeley; and University of California, San Francisco, to take on large-scale scientific challenges in areas like cell biology and infectious disease research.

Building off the successes and lessons learned from the CZ Biohub, CZI is forming a CZ Biohub Network, in which new Biohubs will be created to bring together leading scientific and technology institutions with the goal of pursuing grand scientific challenges on 10- to 15-year time horizons. Applications to create the next CZ Biohub are now closed. Learn more about the selection process.

“Collaboration, risk taking, and staying close  to the scientific community are our best opportunities to accelerate progress in science.”

CORI BARGMANN

HEAD OF SCIENCE

Highlights

Interested in learning more about our work in science? Get the latest information from the links below.

Science

Watch: CZI’s Approach to Accelerating Science with Eric Topol

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Technology

How Single-Cell Biology Helps Us Understand Disease

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CZI Stories

9 Inspiring People We're Celebrating for Women's History Month

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Science

Stories of Collaborative Science

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Science

Can Plants Teach Us About Brain Disease?

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Science

Apply: Essential Open Source Software for Science RFA (Cycle 5)

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Life at CZI

What It’s Like Working on the Rare As One Project

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Science

What Is Sarcoidosis Disease?

Science

Apply: Patient-Partnered Single-Cell Analysis of Rare Pediatric Disease RFA

Science

Apply: Patient-Partnered Rare Neurodegenerative Disease RFA

Diversity, Equity, & Inclusion

Advancing Diversity, Equity and Inclusion in Science

Science

Understanding the Inner Workings of Neurons With AI

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Science

What It’s Like Navigating Rare Disease

Headshots, from left to right, of Mark Zuckerberg, Priscilla Chan and Edward Boyden

Science

Listen: Q&A with Neuroscientist Ed Boyden

Science

Measuring Human Biology in Action

A cluster of fluorescent cells are illuminated with red, green and blue light.

Science

CZI Awards $5 Million to Advance Biomedical Imaging

Science

Watch: CZI Science 5-Year Anniversary Symposium

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Science

Tracking Childhood Diseases at the Cellular Level

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Science

Expanding the
Rare As One Network

Science

How Preprints Accelerated COVID-19 Scientific Breakthroughs

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Life at CZI

Supporting Scientists Globally in Battling Infectious Disease

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Science

A Day in the Life of an Early-Career Researcher

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Science

Rare As One Request for Information: Patient Registry Data Interoperability

Science

Watch: Betting Big on Technology

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Science & Technology

5 Scientists on Pushing the Boundaries of Imaging Tech

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Science & Technology

The Impact of Open Source for Science

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Science

Married Scientists Team Up to Battle Parkinson’s

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SCIENCE

Advancing Diversity and Inclusion in Scientific Open Source

Science

New Grants Support Software Tools and Diversity in Open Source

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COVID-19

Priscilla Chan & Epidemiologist Jessica Malaty Rivera Answer Your COVID-19 Questions

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COVID-19, Science

How One Community Is Restoring Vaccine Trust

COVID-19, Science

Long-Haul COVID-19 Survivors Tell Their Story

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Science

Dr. Kizzmekia Corbett Talks Vaccine Research, Science Diversity With Priscilla Chan

Science

SciDev (Op-ed): Why Sharing Bioimaging Tech is Crucial to Global... SciDev (Op-ed): Why Sharing Bioimaging Tech is Crucial to Global Health

Visualization interface browses segmented cells infected with SARS-CoV-2 virus.

Science

Advancing Imaging Technology Development

Science

Increasing Diversity Among the Next Generation of Science Journalists

Science

STAT (Op-Ed): Use Single-Cell Biology to Shed Light on Pediatric... STAT (Op-Ed): Use Single-Cell Biology to Shed Light on Pediatric Diseases

Science

Expanding Global Access to Bioimaging

Joe DeRisi in white lab coat wears a N-95 mask in a COVID-19 lab.

Science

Meet the Superhero Scientists who
Raced to Respond
to COVID-19

Science

CNN: Inside the Mission to Give the World a Shot

Science

Increasing Diversity in Genomic Research

Science

Leveraging Diversity, Equity and Inclusion in Science

Science

2 Scientists Teaming Up to Prevent Rare Pediatric Diseases

View Photo Story

Science

The Human Cell Atlas, Explained

Science

Why This Neuroscientist Works at CZI

Science

Apply: Rare As One RFA (Cycle 2)

A pie chart titled “Past genomics research lacks ancestral representation” shows people of European ancestry make up 78 percent of study participants.

Science

Expanding the Diversity of the Human Cell Atlas

Science

Three Gen Zs Who Will Change the World

Science

The History of Medical Imaging

Science

WATCH: The Frontiers of Imaging

Science

CZI Awards $32 Million to Advance Biomedical Imaging

Science

Scientists Take a Closer Look at How Disease Works

Science

Scaling Open Infrastructure & Reproducibility in Biomedicine

Science

New Grants for Software Tools & Organizations Advancing Open Science

Science

Q&A: Researchers on How Inflammation Affects Pregnancy

Science

UCSF, CZI, CZ Biohub & State of CA Expand COVID-19 Clinical Testing

Science

Nature Biotechnology: The Making of the Chan Zuckerberg Biohub

Science

How Do We Increase Diversity in STEM?

Science

Using Open Data to Fight COVID-19

Science

Watch: What is the Neurodegeneration Challenge Network?

Science

New Grants to Researchers Studying Neurodegeneration

Science

Fast Company (Op-Ed): How COVID-19 Has Prompted a Revolution i... Fast Company (Op-Ed): How COVID-19 Has Prompted a Revolution in Scientific Publishing

Science

New Effort Helps Track COVID-19 Across California

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Meet Our Team

Two Science Policy team members discussing approaches to support basic science research at CZI.

September 17, 2018 | Kishore Hari and Anne Claiborne, Science Policy, discussing approaches to support basic science research at CZI. Photograph by An Rong Xu.

UCSF MD/PhD student Elizabeth McCarthy handles patient samples in the COVID-19 testing lab at the Chan Zuckerberg Biohub.

Spring 2020. Elizabeth McCarthy, an MD/PhD student at UCSF, handles patient samples. When the COVID-19 pandemic hit, more than 100 students and fellows volunteered to work in the COVID-19 testing lab at the Chan Zuckerberg Biohub. Photograph by Noah Berger, UCSF.

Samantha Scovanner, CZI Science Technology, gives a talk about accelerating science at scale.

August 29, 2018 | Samantha Scovanner, Science Technology, gives a talk about accelerating science at scale. Photograph by Barbara Ries.

CZI Head of Science Cori Bargmann.

September 18, 2017: CZI Head of Science Cori Bargmann. Photograph by Barbara Ries.

Leadership Team Advisory Board

Leadership Team

Cori Bargmann, Head of Science, CZI.

Cori Bargmann Head of Science

Marc Malandro, Vice President of Operations, CZI.

Marc Malandro Vice President of Operations

Phil Smoot, Vice President, Engineering and Head of Science Technology, CZI.

Phil Smoot Vice President, Engineering and Head of Science Technology

Arne Bakker, Director of Meetings and Community, CZI.

Arne Bakker DIRECTOR OF MEETINGS AND COMMUNITY

Patricia Brennan, Director of Product Management for Science Technology, CZI.

Patricia Brennan Director of Product Management for Science Technology

Katja Brose, Program Officer, Neurodegeneration Challenge Network, CZI.

Katja Brose PROGRAM OFFICER, NEURODEGENERATION CHALLENGE NETWORK

Nina Cardoza, Director of Grants and Operations, CZI.

Nina Cardoza DIRECTOR OF GRANTS AND OPERATIONS

Jonah Cool, Program Officer, Single-Cell Biology, CZI.

Jonah Cool PROGRAM OFFICER,
SINGLE-CELL BIOLOGY

Jeff MacGregor, Vice President of Communications, CZI.

Jeff MacGregor VICE PRESIDENT OF COMMUNICATIONS

Bruce Martin, Director of Engineering, CZI.

Bruce Martin DIRECTOR OF ENGINEERING

Ed McCleskey, Program Officer, CZI.

Ed McCleskey PROGRAM OFFICER

Stephani Otte, Program Officer, Imaging, CZI.

Stephani Otte Program Officer, Imaging

Tania Simoncelli, Vice President of Science in Society, CZI.

Tania Simoncelli VICE PRESIDENT OF SCIENCE IN SOCIETY

Dario Taraborelli, Program Officer, Open Science, CZI.

Dario Taraborelli PROGRAM OFFICER, OPEN SCIENCE

Advisory Board

We can’t accelerate science alone. Our Science Advisory Board informs our priorities and allows us to draw on a wide range of expertise as we shape our strategy, establish partnerships, and develop scientific projects.

Tobias Bonhoeffer, Max Planck Institute of Neurobiology, CZI Science Advisory Board.

Tobias Bonhoeffer MAX PLANCK INSTITUTE OF NEUROBIOLOGY

Arthur Levinson, Calico; Former Board Member and Current Advisor, CZI Science Advisory Board.

Arthur Levinson CALICO; FORMER BOARD MEMBER AND CURRENT ADVISOR

Molly Maleckar, Simula Research Laboratory and Advisory Board Chair, CZI Science Advisory Board.

Molly Maleckar SIMULA RESEARCH LABORATORY AND ADVISORY BOARD CHAIR

Yuri Milner, DST Global, CZI Science Advisory Board.

Yuri Milner DST GLOBAL

Shirley Tilghman, Princeton University, CZI Science Advisory Board.

Shirley Tilghman PRINCETON UNIVERSITY

Robert Tjian, Howard Hughes Medical Institute and the University of California, Berkeley, CZI Science Advisory Board.

Robert Tjian HOWARD HUGHES MEDICAL INSTITUTE AND THE UNIVERSITY OF CALIFORNIA, BERKELEY

Harold Varmus, Weill Cornell Medical College, CZI Science Advisory Board.

Harold Varmus WEILL CORNELL MEDICAL COLLEGE

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Join Our Science Mailing List

Be the first to know about new funding opportunities.

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Join Our Team

Explore our job openings.

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Explore Our Grant Resources

Read our Request for Applications.